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KMID : 0370219880320040213
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Yakhak Hoeji
1988 Volume.32 No. 4 p.213 ~ p.221
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MLS Inducible Resistance Mechanism in Bacillus licheniformis EMR-1
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Choi Eung-Chil
Kwak Jin-Hwan
Bernard Weisblum
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Abstract
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Inducible MLS resistance gene of Bacillus licheniformis specified by erm K was subcloned in Bacillus subtilis and the DNA sequence corresponding to its control region was determined. The determinant erm K was in Pvu II=Hind III fragment, which was 1.3 kb. The leader region is capable of forming a complex series of inverted complementary repeat sequences (ICRS) centering on at least six axes of symmetry, some of them mutually exclusive, in a way that resulted ultimately in post-transcriptional unmasking of the ribosome loading site for methylase synthesis.
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